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Household Precautions, Cleaning Aircraft, Flight Crew Precautions, Air Transport of SARS Patients

Interim Guidance on Infection Control Precautions for Patients with Suspected Severe Acute Respiratory Syndrome (SARS) and Close Contacts in Households
April 29, 2003, 10:00 AM ET

Patients with SARS pose a risk of transmission to close household contacts and health care personnel in close contact. The duration of time before or after onset of symptoms during which a patient with SARS can transmit the disease to others is unknown. The following infection control measures are recommended for patients with suspected SARS in households or residential settings. These recommendations are based on the experience in the United States to date and may be revised as more information becomes available.

  1. SARS patients should limit interactions outside the home and should not go to work, school, out-of-home child care, or other public areas until 10 days after the resolution of fever, provided respiratory symptoms are absent or improving. During this time, infection control precautions should be used, as described below, to minimize the potential for transmission.
  2. All members of a household with a SARS patient should carefully follow recommendations for hand hygiene (e.g., frequent hand washing or use of alcohol-based hand rubs), particularly after contact with body fluids (e.g., respiratory secretions, urine, or feces). See the "Guideline for Hand Hygiene in Health-Care Settings" at for more details on hand hygiene.
  3. Use of disposable gloves should be considered for any direct contact with body fluids of a SARS patient. However, gloves are not intended to replace proper hand hygiene. Immediately after activities involving contact with body fluids, gloves should be removed and discarded and hands should be cleaned. Gloves must never be washed or reused.
  4. Each patient with SARS should be advised to cover his or her mouth and nose with a facial tissue when coughing or sneezing. If possible, a SARS patient should wear a surgical mask during close contact with uninfected persons to prevent spread of infectious droplets. When a SARS patient is unable to wear a surgical mask, household members should wear surgical masks when in close contact with the patient.
  5. Sharing of eating utensils, towels, and bedding between SARS patients and others should be avoided, although such items can be used by others after routine cleaning (e.g., washing with soap and hot water). Environmental surfaces soiled by body fluids should be cleaned with a household disinfectant according to manufacturer's instructions; gloves should be worn during this activity.
  6. Household waste soiled with body fluids of SARS patients, including facial tissues and surgical masks, may be discarded as normal waste.
  7. Household members and other close contacts of SARS patients should be actively monitored by the local health department for illness.
  8. Household members or other close contacts of SARS patients should be vigilant for the development of fever or respiratory symptoms and, if these develop, should seek healthcare evaluation. In advance of evaluation, healthcare providers should be informed that the individual is a close contact of a SARS patient so arrangements can be made, as necessary, to prevent transmission to others in the healthcare setting. Household members or other close contacts with symptoms of SARS should follow the same precautions recommended for SARS patients.
  9. At this time, in the absence of fever or respiratory symptoms, household members or other close contacts of SARS patients need not limit their activities outside the home.

Interim Guidance for Cleaning of Commercial Passenger Aircraft Following a Flight with a Passenger with Suspected Severe Acute Respiratory Syndrome (SARS)
May 8, 2003, 2:00 PM EST

Introduction
The Centers for Disease Control and Prevention (CDC) is tracking reports of outbreaks of a respiratory illness called severe acute respiratory syndrome (SARS). CDC has issued two types of notices to travelers: advisories and alerts. A travel advisory recommends that nonessential travel be deferred; a travel alert does not advise against travel, but informs travelers of a health concern and provides advice about specific precautions. CDC updates information on its website on the travel status of areas with SARS as the situation evolves.

This guidance is intended to assist commercial passenger airlines with selection of appropriate post-flight cleaning measures to ensure the safety of their passengers, flight-crew and cleaning personnel. Recommendations are based on standard infection control practices and on available epidemiologic information concerning the infectivity of the etiologic agent of SARS.

Transmission of SARS has been associated with direct contact or close proximity to symptomatic patients. Once passengers have left an aircraft, the main source of infectious particles from a sick passenger will have been removed. However, infection may occur if residual infectious particles on environmental surfaces are brought into direct contact with the eyes, nose or mouth, e.g., by unwashed hands. Therefore, hand hygiene is of primary importance for all personnel working on commercial passenger aircraft.

I. Notification of Ground and Cleaning Crew
CDC has issued guidelines for Airline Flight Crew Members to notify a U.S. Quarantine Station of any ill passengers that meet specified criteria. In addition, the ground and cleaning crews of the airline should be notified at the same time so that preparations can be made for appropriate cleaning of the aircraft after passengers have disembarked.

II. Cleaning and Disinfection
Routine post-flight cleaning of passenger aircraft should incorporate appropriate hand hygiene to minimize risks of disease transmission. CDC has issued interim guidelines for airline cleaning crews conducting routine cleaning on passenger aircraft without a recognized SARS case. Cleaning of aircraft used for air medical (air-ambulance) transport of active SARS patients requires higher level cleaning as described in the air medical transport guidance.

When cleaning commercial passenger aircraft after a flight with a possible SARS patient:

bulletCompressed air that might re-aerosolize infectious material should not be used for cleaning the aircraft. There currently is no evidence to suggest that special vacuuming equipment or procedures are necessary.
bulletCleaning personnel should wear non-sterile disposable gloves while cleaning the passenger cabin and lavatories.
bulletGloves should be removed and discarded if they become soiled or damaged and after cleaning activities are concluded.
bulletHands should be washed with soap and water or an alcohol-based hand sanitizer immediately after gloves are removed.
bulletFrequently touched surfaces in the passenger cabin (e.g., armrests, seatbacks, tray tables, light and air controls, and adjacent walls and windows) and passenger lavatory surfaces should be wiped down with an EPA-registered low- or intermediate-level chemical household germicide* and allowed to air dry in accordance with manufacturer’s instructions.
bulletSpecial cleaning of upholstery, carpets, or storage compartments is not indicated.

III. Occupational health for cleaning crews
Cleaning crew managers should be aware of the symptoms described in the CDC Q & A and should direct cleaning personnel to report to their occupational health service if they develop symptoms within ten days of cleaning an aircraft after a flight that had a possible SARS patient on board.

* There are no disinfectant products currently registered by the U.S. Environmental Protection Agency (EPA) specifically for the inactivation of the newly identified viruses associated with SARS. However, related viruses with physical and biochemical properties similar to the possible SARS agents are known to be readily inactivated by EPA-registered chemical germicides that provide low- or intermediate-level disinfection during general use.

 

Interim Guidelines about Severe Acute Respiratory Syndrome (SARS) For Airline Flight Crew Members
May 8, 2003, 2:00 PM ET

The Centers for Disease Control and Prevention (CDC) is tracking reports of outbreaks of a respiratory illness called severe acute respiratory syndrome (SARS). CDC issues two types of notices to travelers: advisories and alerts. A travel advisory recommends that nonessential travel be deferred; a travel alert does not advise against travel, but informs travelers of a health concern and provides advice about specific precautions. CDC updates information on its website on the travel status of areas with SARS as the situation evolves.

The primary way that SARS appears to spread is by close person-to-person contact. Most cases of SARS have involved people who cared for or lived with someone with SARS, or had direct contact with infectious material (for example, respiratory secretions) from a person who has SARS. Potential ways in which SARS can be spread include touching the skin of other persons or objects that are contaminated with infectious droplets and then touching the eye, nose, or mouth. This can happen when someone who is sick with SARS coughs or sneezes droplets onto themselves, other persons, or nearby surfaces. It is also possible that SARS can be spread more broadly through the air or by other ways that are currently not known.

General infection control precautions

As with many infectious illnesses, the first line of defense to prevent transmission is careful hand hygiene. As a general rule, it is good practice to wash hands frequently with soap and water; if hands are not visibly soiled, alcohol-based hand rubs may be used as an alternative. According to principles of health-care infection control, in a health-care–related emergency, flight crew personnel should wear disposable gloves for direct contact with blood or body fluids of any passenger. However, gloves are not intended to replace proper hand hygiene. Immediately after activities involving contact with body fluids, gloves should be carefully removed and discarded and hands should be cleaned. Gloves must never be washed or reused.

The routine use of personal protective equipment, such as masks, by airline personnel or passengers has drawn considerable attention as a possible approach to prevent transmission of SARS. The effectiveness of masks and other personal protective equipment to prevent transmission of infectious diseases is dependent on proper use for specific tasks involving anticipated contact over a discrete period of time, such as in the health-care setting. It is unclear what benefit routine, prolonged use of personal protective equipment, by airline personnel or the public, would have in settings such as commercial airline flights. For example, a mask may protect the wearer's mouth and nose from large droplets transmitted over short distances between persons. However, it does not prevent transmission with infectious droplets that might occur through direct contact with an infected person or recently touched inanimate objects. When used over long periods, a mask or other piece of personal protective equipment may become contaminated; this presents a particular problem when equipment such as gloves or a mask is being removed after use. Without attention to hand hygiene, a person's hands could easily spread these infectious materials to the eyes, nose, or mouth. Because of these concerns, there is no basis to suggest that the routine use of masks or other personal protective equipment by airline personnel or the public on commercial airliners would be beneficial.

Management of possible cases of SARS during a flight

If you are concerned that a passenger traveling from one of the areas listed above may be ill with a fever or respiratory illness, you should try to keep him or her separated from close contact with the other passengers as much as possible. Provide a surgical mask for the ill passenger to wear if it is available and can be tolerated (i.e., if the severity of the passenger’s respiratory difficulty does not preclude the use of a mask). A surgical mask can reduce the number of droplets coughed into the air. If a surgical mask is not available, provide the passenger with tissues and ask him or her to cover their mouth and nose when coughing. When an ill passenger is unable to wear a surgical mask, flight crew personnel should wear surgical masks when in close contact with the patient. CDC does not recommend the routine use of equipment such as N95 respirators for flight crew personnel. The captain is required by law to report the illness to the nearest U.S. Quarantine Station prior to arrival. Quarantine officials will arrange for appropriate medical assistance to be available when the airplane lands.

While in areas with SARS

To minimize the possibility of infection, you may wish to avoid close contact with large numbers of people as much as possible. CDC does not recommend the routine use of masks or other personal protective equipment while in public areas.

Be aware of the symptoms of SARS (see Basic Information About SARS). If you become ill and you are concerned about SARS, you should contact a health-care provider. Prior to visiting the office or emergency room, tell the health-care provider about your possible exposure so that arrangements can be made, if necessary, to prevent transmission to others in the health-care setting. If you do not have information about a local health-care provider in the country you are visiting, you can contact the U.S. embassy or consulate to ask about finding a health-care provider. Let your employer know you are concerned about possible exposure to SARS and ask your employer about health-care options. Do not travel while sick, and limit your contact with others as much as possible to help prevent the spread of any infectious illness you may have.

When you return home from areas with SARS

CDC is handing out health alert cards to people returning from areas with SARS. If you become sick after you return home, contact a health-care provider prior to visiting their office or emergency room and tell them about your symptoms and the countries you visited. This way arrangements can be made, if necessary, to prevent transmission to others in the health-care setting.

Interim Guidance: Air Medical Transport for Severe Acute Respiratory Syndrome (SARS) Patients
May 8, 2003, 2:30 PM

Introduction

Introduction
The Centers for Disease Control and Prevention (CDC) is tracking reports of outbreaks of a respiratory illness called severe acute respiratory syndrome (SARS). CDC has issued two types of notices to travelers: advisories and alerts. A travel advisory recommends that nonessential travel be deferred; a travel alert does not advise against travel, but informs travelers of a health concern and provides advice about specific precautions. CDC updates information on its website on the travel status of areas with SARS as the situation evolves.

This guidance is intended to assist air medical transport (AMT) service providers using specialized aircraft to transport SARS patients while ensuring the safety of patients and transport personnel. It should not be generalized to commercial passenger aircraft. These interim recommendations are based on standard infection control practices, AMT standards, and epidemiologic information from ongoing investigations of SARS, including experience from air transport of patients during this outbreak.

Currently recommended infection control measures for hospitalized patients with SARS include Standard Precautions (with eye protection to prevent droplet exposure), plus Contact and Airborne Precautions. Respiratory protection using respirators providing at least 95% filtering efficiency (e.g., N-95) with appropriate fit-testing is recommended.

I. Air Transport of SARS Patients, General Considerations

bulletSARS patients should be transported on a dedicated AMT mission minimizing crew size. There should not be any patients or passengers who do not have SARS on board. If a parent is to accompany a sick child, the parent should use protective equipment during transport as described in section IV, below.
bulletIf possible, a single primary-caregiver should be assigned to the SARS patient.
bulletAll SARS patient movement involving U.S. citizens should be coordinated with appropriate state and federal health authorities, including the Centers for Disease Control and Prevention (CDC) (24 hour response number: (770) 488-7100) and the Department of State, before movement begins. International movement of SARS patients might require special approvals by countries that will be over-flown, aircraft-servicing locations, patient rest-stop hospitals, and/or final destinations.

II. Airframe Selection and Cabin Airflow
Cabin airflow characteristics may reduce exposure of occupants to airborne infectious particles; however, based on current understanding of how SARS is transmitted, airflow alone does not provide complete protection of personnel when sharing airspace with an infectious SARS patient. N-95 (or better) respirators are recommended for personnel in any part of an aircraft that shares air (directly or through the ventilation system) with the patient-care cabin.

Fixed-wing, pressurized aircraft:

bulletAMT service providers should consult manufacturer(s) of their aircraft to identify cabin airflow characteristics, including: HEPA filtration and directional airflow capabilities, air outlet location, presence or absence of air mixing between cockpit and patient-care cabin during flight, and the time and aircraft configuration required to perform a post-mission airing-out of the aircraft.
bulletAircraft with forward-to-aft cabin airflow and a separate cockpit cabin are preferred for transport of SARS patients. Aft-to-forward cabin airflow may increase the risk of airborne exposure of cabin and flight deck personnel.
bulletAircraft ventilation should remain on at all times during transport of SARS patients, including during ground delays. Aircraft that re-circulate cabin and flight-deck air without HEPA filtration should not be selected for SARS patient transport.
bulletAircraft that provide space for crew members to perform necessary personal activities (eating, drinking, handling contact lenses, etc.) in an area that does not share air with the patient-care cabin should be selected for flights likely to exceed 4 hours.

Rotor-wing, and non-pressurized aircraft:

bulletIn aircraft with uncontrolled interior airflow such as rotor-wing and small, non-pressurized fixed-wing aircraft, all personnel should wear disposable, N-95 or better respirators during transport of SARS patients.

III. Patient Placement
The in-flight environment might preclude the creation of a true negative pressure space; however, some aircraft designs permit a downwind zone of relative airflow isolation. The airflow of each aircraft should form the basis for litter and seat assignments. In general:

bulletSARS patients should be positioned as far downwind with regard to cabin airflow as possible.
bulletIn AMT aircraft with vertical litter tiers and top-to-bottom airflow, SARS litter patients should be placed in the lowest position in the tier.
bulletAmbulatory SARS patients should be seated next to the cabin sidewall.
bulletIf a non-SARS patient must be transported simultaneously with SARS patient(s), the non-SARS patient must wear an N-95 respirator during transport and should not be positioned downwind from, or within 3 feet of, the SARS patient.
bulletIf several SARS patients are transported, they may be moved as a group (cohorted) in an aircraft that provides appropriate airflow characteristics as described above.

IV. Infection Control
General:

bulletPersonnel should not wear leather or other “flight” gloves while providing patient care.
bulletEating, drinking, application of cosmetics, and handling of contact lenses should not be done in the immediate patient care area.
bulletHandling or storage of medication or clinical specimens should not be done in areas where food or beverages are stored or prepared.

Protective equipment and procedures:

bullet Disposable, non-sterile gloves must be worn for all patient contact.
bulletGloves should be removed and discarded in designated trash bags after patient care is completed (e.g., between patients) or when soiled or damaged.
bulletHands must be washed or disinfected with waterless hand sanitizer immediately after removal of gloves.
bulletDisposable fluid-resistant gowns should be worn for all patient care activity.
bulletGowns should be removed and discarded in designated trash bags after patient care is completed or when soiled or damaged.
bulletGoggles or face-shields must be worn for all patient care within 6 feet of the patient. Corrective eyeglasses alone are not appropriate protection.
bullet Disposable, N-95 respirators are approved for in-flight use. Personnel using N-95 respirators should be fit-tested.
bulletIf air is shared between the cockpit/flight deck and the patient-care cabin, cockpit/flight deck crew should wear disposable N-95 respirators.
bulletFor cockpit crews, aircraft aviator tight-fitting face-pieces capable of delivering oxygen that has not mixed with cabin air may be used in lieu of a disposable N-95 respirator.
bulletPersonal activities that require removal of respirators should not be performed in the patient-care cabin.
bulletPatients should wear a paper surgical mask to reduce droplet production, if tolerated.
bulletOxygen delivery with simple and non-rebreather facemasks may be used for patient oxygen support during flight.
bulletPositive pressure ventilation should be performed using a resuscitation bag-valve mask. If available, units equipped for HEPA or equivalent filtration of expired air should be used.
bullet Cough-generating procedures should be avoided during transport (e.g., nebulizer treatments).

V. Mechanically Ventilated Patients

bulletMechanical ventilators for SARS patients should provide HEPA or equivalent filtration of airflow exhaust.
bulletAMT services should consult their ventilator equipment manufacturer to confirm appropriate filtration capability and the effect of filtration on positive pressure ventilation.

VI. Clinical Specimens

bulletStandard precautions must be used when collecting and transporting clinical specimens.
bulletSpecimens should be stored only in designated coolers or refrigerators.
bulletClinical specimens should be labeled with appropriate patient information and placed in a clean self-sealing bag for storage and transport.

VII. Waste Disposal

bulletDry solid waste (e.g., used gloves, dressings, etc.), should be collected in biohazard bags for disposal as regulated medical waste in accordance with local requirements at the destination medical facility.
bulletWaste that is saturated with blood or body fluids should be collected in leak-proof biohazard bags or containers for disposal as regulated medical waste in accordance with local requirements at the destination medical facility.
bulletSharp items such as used needles or scalpel blades should be collected in puncture resistant sharps containers for disposal as regulated medical waste in accordance with local requirements at the destination medical facility.
bulletSuctioned fluids and secretions should be stored in sealed containers for disposal as regulated medical waste in accordance with local requirements at the destination medical facility. Handling that might create splashes or aerosols during flight should be avoided.
bulletSuction device exhaust should not be vented into the cabin without HEPA or equivalent filtration. Portable suction devices should be fitted with in-line HEPA or equivalent filters. Externally vented suction should not be used during ground operation.
bulletExcretions (feces, urine) may be carefully poured down the aircraft toilet.

VIII. Cleaning and Disinfection

bulletAfter transporting a SARS patient, exits and doors should be closed and aircraft air conditioning turned on at maximum capacity for several minutes in accordance with the airing time specified by aircraft-manufacturers to provide at least one complete air-exchange. Non-pressurized aircraft should be aired out with exits and doors open long enough to ensure a complete air-exchange. Blowers and high-powered fans that might re-aerosolize infectious material should not be used for airing out aircraft.
bulletCleaning should be postponed until airing out is complete.
bulletCompressed air that might re-aerosolize infectious material should not be used for cleaning the aircraft.
bullet Non-patient-care areas of the aircraft should be cleaned and maintained according to manufacturer’s recommendations.
bulletCleaning personnel should wear non-sterile gloves, disposable gowns and face shields while cleaning patient-care areas.
bullet Patient-care areas (including stretchers, railings, medical equipment control panels, and adjacent flooring, walls and work surfaces likely to be directly contaminated during care) should be cleaned using an EPA-registered* hospital disinfectant in accordance with aircraft manufacturer’s recommendations.
bulletSpills of body fluids during transport should be cleaned by placing absorbent material over the spill and collecting the used cleaning material in a biohazard bag. The area of the spill should be cleaned using an EPA-registered hospital disinfectant. Ground service personnel should be notified of the spill location and initial clean-up performed.
bullet Contaminated web seats or seat cushions should be placed in a biohazard bag and labeled with the location and type of contamination for later disposal or cleaning.
bullet Contaminated reusable patient care equipment should be placed in biohazard bags and labeled for cleaning and disinfection at the AMT service medical equipment section.
bulletPersonnel should wear non-sterile gloves, disposable gowns and face shields while cleaning reusable equipment.
bulletReusable equipment should be cleaned and disinfected according to manufacturer’s instructions.

IX. Logistical Planning and Post-Mission Follow-Up

bulletSufficient infection control supplies should be on board to support the expected duration of the mission plus additional time should the aircraft experience maintenance delays or weather diversions.
bulletFlight planning should identify emergency or unexpected diversion airfields, and coordinate with authorities in advance.
bulletUpon mission termination, the AMT team should provide the following information to their medical director: mission number/date; address of the team/aircraft basing; duration of patient transport; names, contact information, and crew positions (including estimated duration of direct patient care provided) of mission personnel.
bulletAMT services should designate individuals responsible for performing post-mission monitoring of mission personnel and reporting results to the AMT service medical director.
bulletMission personnel should be monitored (directly or by telephone) at least once daily for 10 days for evidence of fever or respiratory illness that would require evaluation and follow-up.

* There are no disinfectant products currently registered by the U.S. Environmental Protection Agency (EPA) specifically for the inactivation of the newly identified viruses associated with SARS. However, related viruses with physical and biochemical properties similar to the possible SARS agents are known to be readily inactivated by EPA-registered chemical germicides that provide low- or intermediate-level disinfection during general use.

X. Ground/In-Flight Emergency Procedures
AMT service providers should have a written plan addressing patient handling during in-flight and/or ground emergency situations. Activities such as donning life vests and litter-patient emergency egress may create special exposure risks. Use of N-95 respirators must be weighed against time constraints and on-board emergency conditions (e.g., smoke in the cabin, sudden cabin decompression). Gowns and latex gloves represent a fire/flash hazard and should not be worn during ground or in-flight emergency situations.

Acknowledgements:
This guidance was prepared in cooperation with and with contributions from:

United States Department of Defense

U.S. Transportation Command (USTRANSCOM)
Headquarters Air Mobility Command (HQ AMC)
U.S. Pacific Command (USPACOM)
Headquarters Pacific Air Forces (HQ PACAF)
U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)

United States Department of State
Commission on Accreditation of Air Medical Transport Services (CAMTS)
Aerospace Medicine Association (AsMA)
Air Medical Physician Association (AMPA)
 

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