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Interim Guidance on Infection Control Precautions for Patients with Suspected Severe Acute Respiratory Syndrome (SARS) and Close Contacts in Households
 
April 29, 2003, 10:00 AM ET
Pattients with SARS pose a risk of transmission to close household contacts and health care personnel in close contact. The duration of time before or after onset of symptoms during which a patient with SARS can transmit the disease to others is unknown. The following infection control measures are recommended for patients with suspected SARS in households or residential settings. These recommendations are based on the experience in the United States to date and may be revised as more information becomes available.
  1. SARS patients should limit interactions outside the home and should not go to work, school, out-of-home child care, or other public areas until 10 days after the resolution of fever, provided respiratory symptoms are absent or improving. During this time, infection control precautions should be used, as described below, to minimize the potential for transmission.
  2. All members of a household with a SARS patient should carefully follow recommendations for hand hygiene (e.g., frequent hand washing or use of alcohol-based hand rubs), particularly after contact with body fluids (e.g., respiratory secretions, urine, or feces). See the "Guideline for Hand Hygiene in Health-Care Settings" at for more details on hand hygiene.
  3. Use of disposable gloves should be considered for any direct contact with body fluids of a SARS patient. However, gloves are not intended to replace proper hand hygiene. Immediately after activities involving contact with body fluids, gloves should be removed and discarded and hands should be cleaned. Gloves must never be washed or reused.
  4. Each patient with SARS should be advised to cover his or her mouth and nose with a facial tissue when coughing or sneezing. If possible, a SARS patient should wear a surgical mask during close contact with uninfected persons to prevent spread of infectious droplets. When a SARS patient is unable to wear a surgical mask, household members should wear surgical masks when in close contact with the patient.
  5. Sharing of eating utensils, towels, and bedding between SARS patients and others should be avoided, although such items can be used by others after routine cleaning (e.g., washing with soap and hot water). Environmental surfaces soiled by body fluids should be cleaned with a household disinfectant according to manufacturer's instructions; gloves should be worn during this activity.
  6. Household waste soiled with body fluids of SARS patients, including facial tissues and surgical masks, may be discarded as normal waste.
  7. Household members and other close contacts of SARS patients should be actively monitored by the local health department for illness.
  8. Household members or other close contacts of SARS patients should be vigilant for the development of fever or respiratory symptoms and, if these develop, should seek healthcare evaluation. In advance of evaluation, healthcare providers should be informed that the individual is a close contact of a SARS patient so arrangements can be made, as necessary, to prevent transmission to others in the healthcare setting. Household members or other close contacts with symptoms of SARS should follow the same precautions recommended for SARS patients.
  9. At this time, in the absence of fever or respiratory symptoms, household members or other close contacts of SARS patients need not limit their activities outside the home.

Updated Interim Domestic Infection Control Guidance in the Health-Care and Community Setting for Patients with Suspected SARS
May 1, 2003, 7:00 PM ET

The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have received reports of patients with severe acute respiratory syndrome (SARS). A novel coronavirus, for which CDC recently completed genome sequencing, is believed to be responsible for the global epidemic of SARS. Some close contacts of infected patients, including health-care workers, have developed similar illnesses. In response to these developments, CDC is issuing revised interim guidance concerning infection control precautions in the health-care and community settings. To minimize the potential for transmission, these precautions are recommended, as feasible given available resources, until the epidemiology of disease transmission is better understood.

For all contact with suspect SARS patients, careful hand hygiene is urged, including hand washing with soap and water; if hands are not visibly soiled, alcohol-based handrubs may be used as an alternative to hand washing.

Access www.cdc.gov/handhygiene for more information on hand hygiene.

For the inpatient setting:

If a suspect SARS patient is admitted to the hospital, infection control personnel should be notified immediately. Infection control measures for inpatients (www.cdc.gov/ncidod/hip/isolat/isolat.htm) should include:

bulletStandard precautions (e.g., hand hygiene); in addition to routine standard precautions, health-care personnel should wear eye protection for all patient contact.
bulletContact precautions (e.g., use of gown and gloves for contact with the patient or their environment)
bulletAirborne precautions (e.g., an isolation room with negative pressure relative to the surrounding area and use of an N-95 filtering disposable respirator for persons entering the room)

If airborne precautions cannot be fully implemented, patients should be placed in a private room, and all persons entering the room should wear N-95 respirators. Where possible, a qualitative fit test should be conducted for N-95 respirators; detailed information on fit testing can be accessed at http://www.osha.gov/SLTC/etools/respiratory/oshafiles/fittesting1.html. If N-95 respirators are not available for health-care personnel, then surgical masks should be worn. Regardless of the availability of facilities for airborne precautions, standard and contact precautions should be implemented for all suspected SARS patients.

For the outpatient setting:

bulletPersons seeking medical care for an acute respiratory infection should be asked about possible exposure to someone with SARS or recent travel to a area with SARS. If SARS is suspected, provide and place a surgical mask over the patient’s nose and mouth. If masking the patient is not feasible, the patient should be asked to cover his/her mouth with a disposable tissue when coughing, talking or sneezing. Separate the patient from others in the reception area as soon as possible, preferably in a private room with negative pressure relative to the surrounding area.
bulletAll health-care personnel should wear N-95 respirators while taking care of patients with suspected SARS. In addition, health care personnel should follow Standard precautions (e.g., hand hygiene), Contact precautions (e.g., use of gown and gloves for contact with the patient or their environment) and wear eye protection for all patient contact.

For more information, see the triage guidelines on this website.

For home or residential setting:

Placing a surgical mask on suspect SARS patients during contact with others at home is recommended. If the patient is unable to wear a surgical mask, it may be prudent for household members to wear surgical masks when in close contact with the patient. Household members in contact with the patient should be reminded of the need for careful hand hygiene including hand washing with soap and water; if hands are not visibly soiled, alcohol-based handrubs may be used as an alternative to hand washing. For more information, see the household guidelines on this website.

Case Definition for suspected Severe Acute Respiratory Syndrome (SARS)

Health-care personnel should apply appropriate infection control precautions for any contact with patients with suspected SARS. The case definition for suspected SARS is subject to change, particularly concerning travel history as transmission is reported in other geographic areas; the most current definition can be accessed at the Severe Acute Respiratory Syndrome (SARS) case definition web page.

FACT SHEET
Isolation and Quarantine
May 6, 2003, 4:30 PM EST

To contain the spread of a contagious illness, public health authorities rely on many strategies. Two of these strategies are isolation and quarantine. Both are common practices in public health and both aim to control exposure to infected or potentially infected individuals. Both may be undertaken voluntarily or compelled by public health authorities. The two strategies differ in that isolation applies to people who are known to have an illness and quarantine applies to those who have been exposed to an illness but who may or may not become infected.

Isolation: For People Who Are Ill

Isolation of people who have a specific illness separates them from healthy people and restricts their movement to stop the spread of that illness. Isolation allows for the focused delivery of specialized health care to people who are ill, and it protects healthy people from getting sick. People in isolation may be cared for in their homes, in hospitals, or at designated health care facilities. Isolation is a standard procedure used in hospitals today for patients with tuberculosis (TB) and certain other infectious diseases. In most cases, isolation is voluntary; however, many levels of government (federal, state, and local) have basic authority to compel isolation of sick people to protect the public.

Quarantine: For People Who Have Been Exposed But Are Not Ill

Quarantine, in contrast, applies to people who have been exposed and may be infected but are not yet ill. Separating exposed people and restricting their movements is intended to stop the spread of that illness. Quarantine is medically very effective in protecting the public from disease.

States generally have authority to declare and enforce quarantine within their borders. This authority varies widely from state to state, depending on the laws of each state. The Centers for Disease Control and Prevention (CDC), through its Division of Global Migration and Quarantine, also is empowered to detain, medically examine, or conditionally release individuals suspected of carrying certain communicable diseases. This authority derives from section 361 of the Public Health Service Act (42 U.S.C. 264), as amended.

SARS and Isolation

SARS patients in the United States are being isolated until they are no longer infectious. This practice allows patients to receive appropriate care, and it contains the potential spread of the illness. Those who are more severely ill are being cared for in hospitals. Those whose illness is mild are being cared for at home. Individuals being cared for at home have been asked to avoid contact with other people and to remain at home until 10 days after the resolution of fever, provided respiratory symptoms are absent or improving. (For more information on SARS infection control precautions, visit CDC's SARS Web site.)

SARS and Quarantine

To date, CDC has recommended isolation of individuals with SARS, but has not compelled quarantine or isolation of these individuals.

Questions and Answers on Executive Order and Interim Final Rule
April 14, 2003, 1:00 PM EST

Q.1. What is CDC’s quarantine authority?

A.1. Title 42 United States Code Section 264 (Section 361 of the Public Health Service Act) gives the Secretary of Health and Human Services (HHS) responsibility for preventing the introduction, transmission, and spread of communicable diseases from foreign countries into the United States and within the United States and its territories/possessions. This statute is implemented through regulations found at 42 CFR Parts 70 and 71. Under its delegated authority, the CDC is empowered to detain, medically examine, or conditionally release individuals suspected of carrying a communicable disease.

Q.2. Why was an Executive Order necessary?

A.2. Under the procedures required under the PHS Act, the list of diseases for which quarantine is authorized must first be specified in an Executive Order of the President, on recommendation of the HHS Secretary. By amending the list to include SARS, HHS is simply taking the pragmatic step of readying all options as we continue to tackle this disease.

Q.3. What does the Executive Order accomplish?

A.3. In the event a passenger infected with SARS were to arrive in the United States on board an international flight, the Executive Order provides HHS with clear legal authority to detain or isolate the non-compliant passenger and prevent the passenger from infecting others. This authority would only be used if someone posed a threat to public health and refused to cooperate with a voluntary request.

Q.4. Were any other diseases added to the list?

A.4. No, the Executive Order only added SARS to the list of communicable diseases for which isolation and/or quarantine is authorized. The other diseases: Cholera; Diphtheria; infectious Tuberculosis; Plague; Smallpox; Yellow fever; and Viral Hemorrhagic Fevers, have appeared on the list since 1983.

Q.5. Why did CDC issue a new rule?

A.5. Amending the quarantine regulations to incorporate the Executive Order by reference eliminates the unnecessary administrative delay in the future of publishing another regulation if the list needs to be changed again. These revisions also serve the dual capacity of giving HHS the flexibility to better protect the public against the increased threat of a new microbe deliberately used in a bioterrorism event.

Q.6. Why was this new rule issued without notice and comment?

A.6. This rule was issued on an interim final basis with no prior notice and comment and no delay in effective date. As of April 12, 2003, the WHO has reported 2960 cases and 119 deaths of severe pneumonia-like illness of unknown origin in a growing number of countries. Several countries, including Canada, Hong Kong SAR, and Singapore have instituted maximum health measures, including quarantine, to prevent the further spread of the disease. The CDC is currently investigating 188 suspected cases of the disease in the United States. Accordingly, appropriate public health control measures including quarantine need to be available immediately to protect against this threat.

Q.7. Have other countries taken similar steps?

A.7. Several countries, including Canada, Hong Kong SAR, and Singapore have instituted maximum health measures, including quarantine, to prevent the further spread of the disease. Ontario, Canada has taken the additional step of making SARS a reportable, virulent, communicable disease under Ontario’s Health Protection and Promotion Act. This allows Canadian public health officers to issue orders to stop infected people from engaging in activities that transmit SARS.

Q.8. Have these new quarantine powers been used yet?

A.8. CDC has not compelled the isolation or quarantine of anyone for SARS. CDC routinely uses the authority of the PHS Act to monitor passengers arriving into the United States for communicable diseases.

Q.9. When was this quarantine power last used?

A.9. The last litigated case involving the involuntary quarantine of a passenger arriving into the United States occurred in 1963 and involved a suspect case of smallpox. On the other hand, CDC routinely temporarily detains incoming planes and interviews passengers for health reasons. For example, CDC temporarily detained an incoming plane and interviewed passengers in Seattle in December 2001 to verify that a report of smallpox aboard the flight was in fact a hoax.

Q.10. When does CDC intend to use these quarantine powers?

A.10. In general, HHS defers to the state and local health authorities in their primary use of their own separate quarantine powers. Based upon long experience and collaborative working relationships with our state and local partners, CDC would continue to anticipate the need to use this federal authority to actually quarantine a person only in rare situations, like events at ports of entry or in similar time-sensitive settings.
 

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